Restricting Insulin Doses Increases Mortality Risk

Thursday, February 28th, 2008

A new study led by researchers at the Joslin Diabetes Center has found that women with type 1 diabetes who reported taking less insulin than prescribed had a three-fold increased risk of death and higher rates of disease complications than those who did not skip needed insulin shots. The new ...

Genetic Deficiency Of Glycogen Synthase Kinase-3Beta Corrects Diabetes In Mouse Models Of Insulin Resistance

Wednesday, February 20th, 2008

Diabetes is often characterized by a failure of insulin production by pancreatic Beta-cells to properly regulate glucose homeostasis. Insulin resistance can lead to ?-cell failure, and our studies have focused on elucidating the mechanisms involved in this postnatal failure. This week in the open-access journal PLoS Biology, Katsuya Tanabe, James Woodgett, ...