Genetic Deficiency Of Glycogen Synthase Kinase-3Beta Corrects Diabetes In Mouse Models Of Insulin Resistance
Wednesday, February 20th, 2008Diabetes is often characterized by a failure of insulin production by pancreatic Beta-cells to properly regulate glucose homeostasis. Insulin resistance can lead to ?-cell failure, and our studies have focused on elucidating the mechanisms involved in this postnatal failure. This week in the open-access journal PLoS Biology, Katsuya Tanabe, James Woodgett, ...