FDA approves SPA Protocol Amendment for Lucanix Phase III clinical trial
NovaRx Corporation announced today that the Company has successfully negotiated and received FDA approval for a Special Protocol Assessment (SPA) Protocol Amendment to the pivotal Lucanix® Phase III clinical trial in patients with Non-Small Cell Lung Cancer (NSCLC). The amendment will expand patient eligibility and [...]
Ligand to Acquire Metabasis for Cash and Contingent Value Rights
Ligand Pharmaceuticals Incorporated (NASDAQ: LGND – News) and Metabasis Therapeutics, Inc. (NASDAQ: MBRX – News) announced today they have entered into a definitive merger agreement under which Ligand will acquire all of the outstanding shares of Metabasis.
Under the transaction, Metabasis stockholders will receive a cash payment [...]
International Stem Cell Corporation (OTCBB:ISCO) announced that its human parthenogenetic stem cell lines will be used in Germany in studies aimed at creating specific cell types to treat human neural diseases such as Parkinson’s disease.
The work will be headed by Dr. Albrecht Mueller of the University of Wuerzburg, Wuerzburg, Germany under a Material Transfer Agreement [...]
Adult stem cells may provide an explanation for the cause of a Hutchinson-Gilford Progeria Syndrome (HGPS), a rare disease that causes premature aging in children, according to researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH). These findings, the first to indicate a biological basis for the clinical features [...]
The reductionist goal of cell biology is to explain cellular activities in physical-chemical terms. To do this, one needs to quantify molecular concentrations and aggregation states in living cells as they execute and regulate various complex processes.
For a complex cellular activity like migration, which is characterized by highly localized, transient component processes, the need for [...]
The energy from sunlight falling on only 9 percent of California’s Mojave Desert could power all of the United States’ electricity needs if the energy could be efficiently harvested, according to some estimates. Unfortunately, current-generation solar cell technologies are too expensive and inefficient for wide-scale commercial applications.
A team of Northwestern University researchers has developed a [...]
Advanced Cell Technology, Inc. (OTCBB: ACTC) reported for the first time a robust and highly efficient process for the generation of high-purity hepatocytes (liver cells). The research, described online (ahead of print) in the journal STEM CELLS, signifies a significant step towards the efficient generation of hepatocytes for use in regenerative medicine and drug discovery. [...]
Stem Cell Therapeutics Corp. (“SCT”) (TSX VENTURE:SSS) is pleased to announce favorable results from the investigator led BETAS (Beta-hCG + Erythropoietin in Acute Stroke), Phase IIa, open label, safety trial conducted at the University of California, Irvine and Hoag Presbyterian Memorial Hospital, Newport Beach, CA. This trial is the first to test the safety of [...]
Scientists at a US biotechnology company implanted immature beta-cells derived from human embryonic stem cells (hES cells) into mice and showed that they generated insulin-secreting cells that responded to raised blood sugar. They hope the discovery will one day lead to a renewable source of insulin-producing cells for the treatment of diabetes.
The study is published [...]
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