With The Help Of Short RNA Strand Exposed Skin Cells Protect Body From Bacteria, Dehydration And Even Cancer

Monday, March 3rd, 2008

Every minute, 30,000 of our outermost skin cells die so that we can live. When they do, new cells migrate from the inner layer of the skin to the surface of it, where they form a tough protective barrier. In a series of elegant experiments in mice, researchers at Rockefeller ...

Quiet Developmental Gene Turned Into A Potent Driver Of T-Cell Lymphoma By Inverted DNA

Thursday, February 28th, 2008

A gene crucial for embryonic development can quickly become a potent cancer promoter in adult mice after a genetic misalignment, according to researchers from Fox Chase Cancer Center, causing white blood cells to become cancerous spontaneously. In the March 1 issue of the journal Cancer Research, the researchers detail how a ...

New Direction In HIV Vaccine Design

Thursday, February 28th, 2008

Researchers at The Scripps Research Institute have developed a new two-punch strategy against HIV and they have already successfully tested aspects of it in the laboratory. Their study, which appears this week in the online Early Edition of the Proceedings of the National Academy of Sciences (PNAS), may re-energize attempts to ...

Common Hypertension Drug Found To Reduce Cocaine Cravings

Thursday, February 28th, 2008

Researchers from Boston University School of Medicine and Harvard Medical School have found that diltiazem, a drug used in the treatment of high blood pressure, reduces cocaine cravings in a rat model. These findings will appear in the March issue of the leading medical journal Nature Neuroscience. Previous work showed that ...

MIT Student Invents Knock-Out Punch For Antibiotic Resistance

Thursday, February 28th, 2008

MIT graduate student and synthetic biologist Timothy Lu is passionate about tackling problems that pose threats to human health. His current mission: to destroy antibiotic-resistant bacteria. The 27-year-old M.D. candidate and Ph.D. in the Harvard-MIT Division of Health Sciences and Technology received the prestigious $30,000 Lemelson-MIT Student Prize for inventing processes ...

Potential Drug Targets Found In Scripps Study Of Sepsis In Mice

Thursday, February 28th, 2008

"We have identified a key connection of signaling pathways in the cascade of events leading to sepsis. This defines a crucial point where the immune system spirals out of control to cause severe sepsis and where there is an opportunity for therapeutic intervention," says Scripps Research Professor Wolfram Ruf, who ...

Genome-Wide Open Chromatin From Next Generation Sequencing Integrated By Genomatix

Tuesday, February 26th, 2008

Genomatix Software GmbH, a Systems Biology company focussed on high quality annotation and the understanding of gene regulation, has begun showcasing its abilities in the analysis of data generated by Next Generation Sequencing (NGS) technology. Allan P. Boyle et al published in Cell some remarkable work on "High-Resolution Mapping and Characterization ...

Honey Bee Invaders Exploit The Genetic Resources Of Their Predecessors

Tuesday, February 26th, 2008

Like any species that aspires to rule the world, the honey bee, Apis mellifera, invades new territories in repeated assaults. A new study demonstrates that when these honey bees arrive in a place that has already been invaded, the newcomers benefit from the genetic endowment of their predecessors. The findings appear ...

Proteins That Help Bacteria Put Up A Fight Identified By Scientists

Tuesday, February 26th, 2008

Scientists have identified the role of two proteins that contribute to disease-causing bacteria cells' versatility in resisting certain classes of antibiotics. The finding is a step toward development of drug therapies that could target bacterial resistance at its cellular source. Before researchers can design such drugs, they must understand all of ...