Archive for the ‘Schizophrenia’ Category
Monday, February 18th, 2008
A genetic variant in the Reelin gene increases the chances of developing schizophrenia but not men. At the Hebrew University of Jerusalem and the University of Oxford, researchers conducted a study of this issue in the Ashkenzi Jewish population. They confirmed their findings through a global collaboration including populations and ...
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Thursday, November 1st, 2007
Under conditions where common sense and logic conflict, people with schizophrenia reason more logically than healthy individuals, a new study has found.
The researchers were testing a hypothesis that in schizophrenia there is an enhancement of theoretical over practical reasoning. They looked at whether tasks that are correct from a theoretical ...
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Thursday, November 1st, 2007
BioLineRx Ltd. (TASE:BLRX), today announced positive interim results from an ongoing Phase 2 trial of BL-1020, a GABA enhanced antipsychotic. The study is an open-label, multi-center, 6-week trial conducted in hospitalized patients with treatment resistant schizophrenia, in which BL-1020 showed statistically significant efficacy with minimal side effects. The assessment was ...
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Thursday, November 1st, 2007
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (J&JPRD) announced that it has submitted a New Drug Application to the U.S. Food and Drug Administration (FDA) for paliperidone palmitate, an investigational, once-monthly atypical antipsychotic intramuscular injection, for the treatment of schizophrenia and the prevention of recurrence of the symptoms of ...
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Tuesday, October 16th, 2007
Yesterday, Janssen-Cilag presented for the first time in Europe, new preliminary data that show acutely ill, hospitalised patients with schizophrenia experienced significant improvement in symptoms after taking INVEGA® (paliperidone prolonged-release tablets) as compared to Seroquel® (quetiapine) or placebo. Symptom improvement was observed with INVEGA five days into therapy and continued ...
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Tuesday, October 16th, 2007
Forest Laboratories, Inc. (NYSE: FRX) and Gedeon Richter announced preliminary top-line results from a U.S. conducted randomized, double-blind, three-arm placebo-controlled study of RGH-188, a novel antipsychotic, in 389 schizophrenia patients. The protocol-specified primary endpoint was change from baseline to Week 6 on the Positive and ...
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Wednesday, September 12th, 2007
Scientists at Johns Hopkins have developed a mouse model for schizophrenia in which a mutated gene linked to schizophrenia can be turned on or off at will.
The researchers developed the transgenic mouse by inserting the gene for mutant Disrupted-In-Schizophrenia-1 (DISC-1) into a normal mouse, along with a promoter that enables ...
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Wednesday, August 22nd, 2007
Scientists know that information travels between brain cells along hairlike extensions called axons. For the first time, researchers have found that axons don't just transmit information -- they can turn the signal up or down with the right stimulation.
This finding may help scientists develop treatments for psychiatric disorders such as ...
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Sunday, August 12th, 2007
Scientists have provided new insight into how a gene is related to schizophrenia. In a study to be published in the August 17 issue of the Journal of Biological Chemistry, Amanda J. Law, Medical Research Council Fellow and Associate Professor at the University of Oxford, United Kingdom, and Visiting Scientist ...
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