Archive for the "Neurology / Neuroscience" Category

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Identification Of A Key Gene Required For Brain Neural Circuit Formation

An international team of scientists, lead by Dr. Frederic Charron at the IRCM, and Drs Ami Okada, Sue McConnell, and Marc Tessier-Lavigne in the USA, have made a discovery which could help treat spinal cord injuries and neurodegenerative diseases. This new finding will be published in the next issue of the prestigious scientific journal Nature.
The [...]

News Tips From The Journal Of Neuroscience

1. Making Fly Synapses with and without Glutamate Receptors
Andreas Schmid, Gang Qin, Carolin Wichmann, Robert J. Kittel, Sara Mertel, Wernher Fouquet, Manuela Schmidt, Manfred Heckmann, and Stephan J. Sigrist
A small army of structural proteins is needed to cluster and anchor postsynaptic receptors, ion channels, and other molecules to the right spots at synapses. This week, [...]

Brainstem Abnormality Link To SIDS Stronger Than Previously Indicated

Preliminary research suggests that brainstem abnormalities involving certain serotonin pathways in the brain may play a more important role in SIDS than previously thought, according to an article in the November 1 issue of JAMA.
Sudden infant death syndrome (SIDS) is the leading cause of postneonatal infant death in the United States. [...]

Gene Therapy A Possibility For Metachromatic Leukodystrophy?

Metachromatic leukodystrophy (MLD) is an inherited disease that causes progressively more severe neurological defects that result in death early in life. Individuals with MLD have a genetic defect that means they lack a protein known as ARSA. There are currently no therapies for MLD, largely because the barrier between the blood [...]

Decreased TGF-beta Signaling Might Make You Demented

The physical changes that occur in the brain of patients with Alzheimer’s disease (AD), the most common cause of dementia in the elderly, have been well characterized, but the cause(s) of this disease and the development of therapies has remained elusive. Now, in a study appearing in the November issue of the [...]