Archive for the ‘Liver Disease / Hepatitis’ Category

The 58th Annual Meeting Of The American Association For The Study Of Liver Diseases, Boston, Nov. 2-6

Tuesday, October 16th, 2007

The Liver Meeting is the premier meeting in the science and practice of hepatology, including the latest findings on new drugs, novel treatments, and the results from pilot and multicenter studies. Approximately 10 percent of Americans have some form of liver disease, and the diseases strike disproportionately ...

Fighting The Treacherous Hepatitis B

Tuesday, October 2nd, 2007

One in four people who are chronically infected with hepatitis B will die from its impact if untreated, but a team of researchers at the Stanford University School of Medicine has identified the most cost-effective way of fighting this treacherous infection. Those infected with hepatitis B often don't know it, because ...

Pharmasset Commences Dosing In Phase 3 Registration Studies Of Clevudine For HBV

Tuesday, October 2nd, 2007

Pharmasset, Inc. (Nasdaq: VRUS) has commenced dosing in Phase 3 registration clinical trials of clevudine for the treatment of chronic hepatitis B virus (HBV) infection. Clevudine is an oral, once-daily pyrimidine nucleoside analog that has previously been evaluated in 14 clinical trials in ...

Sorafenib Increases Survival In Patients With Late-Stage Liver Cancer

Friday, September 28th, 2007

The oral multikinase inhibitor inhibitor sorafenib (Nexavar) significantly improves survival compared to placebo in patients with advanced hepatocellular carcinoma, according to phase III results reported at the 14th European Cancer Conference (ECCO). "Available systemic therapies for hepatocellular carcinoma have no proven survival advantage," Josep Llovet, MD, Director of Hepatocellular Research in ...

US FDA Fast Tracks PI-88 For The Treatment Of Post Resection Liver Cancer

Tuesday, September 25th, 2007

Progen Pharmaceuticals Limited (ASX: PGL; Nasdaq: PGLA) announced that its investigational anti-cancer drug PI-88 has been awarded Fast Track status by the U.S. Food and Drug Administration (FDA). The fast track designation has been granted to PI- 88 for the prevention of tumor recurrence ...

European Union’s CHMP Issues Positive Opinion On PEGINTRON(TM) Combination Therapy For Retreating Hepatitis C Patients Who Failed Previous Therapy

Tuesday, September 25th, 2007

Schering-Plough Corporation (NYSE: SGP) reported that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMEA) has issued a positive opinion recommending approval of combination therapy with PEGINTRON(TM) (peginterferon alfa-2b, 1.5 mcg/kg once weekly) and REBETOL(R) ...

Nexavar Receives Positive Opinion From European Committee For Medicinal Products For Human Use For Treatment Of Liver Cancer

Sunday, September 23rd, 2007

Bayer HealthCare Pharmaceuticals (NYSE: BAY) and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that the European Committee for Medicinal Products for Human Use (CHMP) has issued a positive opinion, recommending to grant marketing authorization for Nexavar(R) (sorafenib) tablets for the treatment of patients with ...

Potential Blood Test For Early Detection Of Liver Cancer

Friday, September 21st, 2007

In the face of an emerging liver cancer crisis in Asia, researchers at the Chinese University of Hong Kong have developed a test that could help millions. Due to widespread hepatitis B virus (HBV) infection, nearly 10 percent of China's population is at high risk for hepatocellular carcinoma (HCC), a ...

Progen Engages Leading CRO To Assist With Phase 3 Trial Of PI-88

Friday, August 17th, 2007

Progen Pharmaceuticals Limited (ASX: PGL; Nasdaq: PGLA) today announced it has executed an agreement with Quintiles, the world's largest Contract Research Organisation, to utilise their services for a number of clinical development- related projects. This agreement includes the execution of the Phase 3 clinical trial of anti-cancer drug PI-88 for ...