Archive for the ‘Huntingtons Disease’ Category
Sunday, August 26th, 2007
A major breakthrough in the understanding and potential treatment of Huntington's disease has been made by scientists at the University of Leeds.
Researchers in the University's Faculty of Biological Sciences have discovered that one of the body's naturally occurring proteins is preventing 57 genes from operating normally in the brains of ...
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Tuesday, July 31st, 2007
Medivation, Inc. (Nasdaq: MDVN) today announced treatment of the first patient in its Phase 2 trial of Dimebon(TM) to treat Huntington's disease. Medivation has expanded patient enrollment in the trial by 20 percent -- to 90 patients -- in order to enhance the ability to detect differences between Dimebon and ...
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Friday, April 27th, 2007
Huntington's disease, an inherited neurodegenerative disorder that affects roughly 30,000 Americans, is incurable and fatal. But a new discovery about how cells repair their DNA points to a possible way to stop or slow the onset of the disease. The research was funded by the National Institutes of Health (NIH). ...
Posted in Biology / Biochemistry, Genetics, Huntingtons Disease, Neurology / Neuroscience | No Comments »
Sunday, April 8th, 2007
McMaster scientists are very close to defining small molecule drugs that should be able to redirect the huntingtin protein from accumulating in the wrong place within brain cells, which could potentially translate to a therapy for Huntington's Disease (HD).
There is currently no way to stop or reverse the progression of ...
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Friday, April 6th, 2007
To function, each living cell needs both to build new and to degrade old or damaged proteins. To accomplish that, a number of intracellular systems work in concert to keep the cell healthy and from clogging up with damaged proteins. When proteins or peptides mutate, they can present major problems ...
Posted in Biology / Biochemistry, Huntingtons Disease | No Comments »
Monday, December 4th, 2006
Mayo Clinic researchers have discovered a protein interaction that may explain how the deadly Huntington's disease affects the brain. The findings, published in and featured on the cover of the current issue of Human Molecular Genetics, show how the mutated Huntington's protein interacts with another protein to cause dramatic accumulation ...
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Thursday, November 16th, 2006
Medivation, Inc. (Amex: MDV) today announced updated clinical development plans and milestones for its three programs in Alzheimer's disease, Huntington's disease and hormone-refractory prostate cancer.
Dimebon(TM) for Alzheimer's and Huntington's Diseases
"Given the safety and significant efficacy data generated in our recently completed Phase 2 trial in Alzheimer's ...
Posted in Alzheimers / Dementia, Clinical Trials / Drug Trials, Huntingtons Disease, Prostate | No Comments »
