Archive for the ‘Cystic Fibrosis’ Category
Friday, February 22nd, 2008
Cystic fibrosis (CF), a hereditary disorder causing thick mucous production and frequent lung infections, is associated with a high mortality rate primarily due to lung failure. Although it is known that mutations in the CFTR gene cause the disease, variations in other genes between individuals with CF modify the severity ...
Posted in Cystic Fibrosis | No Comments »
Friday, August 17th, 2007
Gilead Sciences, Inc., one of the world's largest biopharmaceutical companies, and Parion Sciences, Inc., a development-stage pharmaceutical company, announced they will co-develop Parion 680, a compound that could become an important new drug in treating the basic defect in cystic fibrosis. This product was identified as part of a $1.7 ...
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Friday, April 27th, 2007
Using a new type of drug that targets a specific genetic defect, researchers at the University of Pennsylvania School of Medicine, along with colleagues at PTC Therapeutics Inc. and the University of Massachusetts Medical School, have for the first time demonstrated restoration of muscle function in a mouse model of ...
Posted in Blood / Hematology, Cystic Fibrosis, Genetics, Muscular Dystrophy | No Comments »
Thursday, April 26th, 2007
Researchers from the Schulich School of Medicine & Dentistry at The University of Western Ontario , working with a group from Edinburgh, have discovered a way to kill the cystic fibrosis superbug, Burkholderia cenocepacia. These investigators, under the leadership of Dr. Miguel Valvano, Department of Microbiology and Immunology, have had ...
Posted in Biology / Biochemistry, Cystic Fibrosis, Infectious Diseases | No Comments »
Saturday, April 21st, 2007
Researchers at the University of Pennsylvania School of Medicine have discovered that an enzyme produced by lung-infecting bacteria further shuts down a protein that is defective in cystic fibrosis patients. The disruption to this protein that conveys ions from lung cells to airways causes thick mucus to buildup inside the ...
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Saturday, April 21st, 2007
The Cystic Fibrosis Foundation announced today the kick-off of GREAT STRIDES, a national walk benefiting critical cystic fibrosis research, education and care programs. GREAT STRIDES, now in its 19th year, is the largest CF fund-raiser and seeks to raise $36 million nationwide in 2007.
Tens of thousands of walkers are expected ...
Posted in Cystic Fibrosis, Respiratory / Asthma | No Comments »
Thursday, April 19th, 2007
While working to find novel ways to treat the life-threatening disease of cystic fibrosis, researchers at the University of North Carolina have discovered that the rhythmic motion of the lungs during normal breathing is a critical regulator of the clearance of bacteria and other noxious materials. Their research, funded by ...
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Wednesday, April 18th, 2007
A new technology developed at the University of Toronto is revealing biochemical processes responsible for diseases such as cystic fibrosis and could one day pave the way for pharmaceutical applications.
A study appearing in the April 13 issue of Molecular Cell describes how U of T and Johns Hopkins University researchers ...
Posted in Biology / Biochemistry, Cancer / Oncology, Cystic Fibrosis, MRSA / Drug Resistance | No Comments »
Thursday, April 12th, 2007
Melbourne based biotechnology company Cryptopharma Pty Ltd announced that its inflammation drug candidate, CP-92, has been chosen as a lead and will be advanced into development after very positive results from laboratory testing.
The product is an Australian innovation and has shown high levels of activity in animal models of inflammatory ...
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