Astellas Terminates Agreement On Acute Heart Failure Agent Carperitide

Astellas Pharma Inc. today announced that its US affiliate, Astellas US LLC, has terminated its license agreement with Daiichi Asubio Pharma Co., Ltd. (Tokyo) regarding North American and European Union rights to carperitide for the treatment of acute heart failure.

Astellas US LLC’s predecessor, Fujisawa Healthcare, Inc. and Daiichi Asubio Pharma’s predecessor, Daiichi Suntory Pharma Co., Ltd. executed the license agreement in May, 2003. Astellas’ affiliate in the US had conducted some clinical trials using carperitide in the United States but after reassessing competitive circumstances and market potential, decided to discontinue carperitide development. As a result of this decision, both parties have agreed to terminate the license agreement.

Astellas recognizes cardiovascular disorders as an important category through the development of pipeline compounds and the marketing of such products as Adenoscan(R), a pharmacologic stress agent in pharmaceutical stress testing; Vaprisol(R) for euvolemic hyponatremia; and Adenocard(R), an anti-arrhythmic agent in the United States.

About Astellas Pharma Inc.

Astellas Pharma Inc., located in Tokyo, Japan, is a pharmaceutical company dedicated to improving the health of people around the world through the provision of innovative and reliable pharmaceutical products. In April 2005, the company was formed through the merger of Fujisawa Pharmaceutical Co., Ltd. and Yamanouchi Pharmaceutical Co., Ltd. The organization is committed to becoming a global mega pharmaceutical company by combining outstanding R&D and marketing capabilities and continuing to grow in the world pharmaceutical market. For more information on Astellas Pharma Inc., please visit the company’s website at http://www.astellas.com.

Astellas Pharma Inc.
http://www.astellas.com

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